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Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $47 | In Stock | |
200 mg | $68 | In Stock | |
500 mg | $117 | In Stock | |
1 mL x 10 mM (in DMSO) | $30 | In Stock |
Description | Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). |
In vivo | The chemical properties of Liothyronine Sodium are nearly identical to those of Triiodothyronine, acting on thyroid hormone receptors alpha and beta-1. As the most potent form of thyroid hormone, Liothyronine Sodium can increase the basal metabolic rate, affect protein synthesis, and enhance the body's sensitivity to catecholamines (such as adrenaline). |
Alias | Triostat, T3 Sodium salt, Sodium L-3,3',5-triiodothyronine, Cytomel, 3,3',5-Triiodo-L-thyronine sodium |
Molecular Weight | 672.96 |
Formula | C15H11I3NNaO4 |
Cas No. | 55-06-1 |
Smiles | [Na+].N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C([O-])=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (22.29 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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